LAB TESTS IN KAWASAKI DISEASE
THERE IS NO SINGLE CONFIRMATORY LAB TEST FOR KAWASAKI DISEASE.
- Leukocytosis with neutrophilia and immature forms
- Elevated ESR, CRP
- Abnormal plasma lipids
- Thrombocytosis after week 1
- Sterile pyuria
- Elevated serum transaminases & GGT
- Pleocytosis of cerebrospinal fluid
- Leukocytosis in synovial fluid
- Supplemental laboratory criteria include
- albumin <3.0 g/dL,
- anemia for age
- elevation of alanine aminotransferase,
- Platelets after 7 days >450 000/mm3
- White blood cell count >15 000/mm3
- Urine >10 white blood cells/high-power field.
- Mild to moderate elevations in serum transaminases occur in 40% of patients and mild hyperbilirubinemia in 10%
- Plasma GGT is elevated in 67% of patients
- Hypoalbuminemia is common and is associated with more severe and more prolonged acute disease
- Urinalysis reveals intermittent mild to moderate sterile pyuria in 33% of patients, although
- Suprapubic urine generally does not show pyuria, which suggests urethritis
- Lumbar puncture, 50% demonstrate evidence of aseptic meningitis with a predominance of mononuclear cells, as well as normal glucose and protein levels.