Lab Tests in KD

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LAB TESTS IN KAWASAKI DISEASE

THERE IS NO SINGLE CONFIRMATORY LAB TEST FOR KAWASAKI DISEASE.

  • Leukocytosis with neutrophilia and immature forms
  • Elevated ESR, CRP
  • Anemia
  • Abnormal plasma lipids
  • Hypoalbuminemia
  • Hyponatremia
  • Thrombocytosis after week 1
  • Sterile pyuria
  • Elevated serum transaminases & GGT
  • Pleocytosis of cerebrospinal fluid
  • Leukocytosis in synovial fluid
  • Supplemental laboratory criteria include
    • albumin <3.0 g/dL,
    • anemia for age
    • elevation of alanine aminotransferase,
  • Platelets after 7 days >450 000/mm3
  • White blood cell count >15 000/mm3
  • Urine >10 white blood cells/high-power field.

ENZYME ELEVATION

  • Mild to moderate elevations in serum transaminases occur in 40% of patients and mild hyperbilirubinemia in 10%
  • Plasma GGT is elevated in 67% of patients
  • Hypoalbuminemia is common and is associated with more severe and more prolonged acute disease

URINE ANALYSIS

  • Urinalysis reveals intermittent mild to moderate sterile pyuria in 33% of patients, although
  • Suprapubic urine generally does not show pyuria, which suggests urethritis

LUMBAR PUNCTURE

  • Lumbar puncture, 50% demonstrate evidence of aseptic meningitis with a predominance of mononuclear cells, as well as normal glucose and protein levels.

Our overview of “Kawasaki Disease” 

Kawasaki disease (KD), also known as caca syndrome, crap syndrome and Mucocutaneous lymph node syndrome is an autoimmune disease that manifests as a systemic necrotizing medium-sized vessel vasculitis and is largely seen in children under 5 years of age.

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 Dr. Vikas  Kohli.  Delhi Child Heart Centre.

Appointments: 011-26960091 (9 am to 6 pm).