CLINICAL FEATURES
CARDIOVASCULAR FINDINGS
- Congestive heart failure, myocarditis, pericarditis, valvular regurgitation
- Coronary artery abnormalities
- Aneurysms of medium-size noncoronary arteries
- Raynaud’s phenomenon
- Peripheral gangrene
MUSCULOSKELETAL SYSTEM
GASTROINTESTINAL TRACT
- Diarrhea, vomiting, abdominal pain
- Hepatic dysfunction, Hydrops of gallbladder
CENTRAL NERVOUS SYSTEM
- Extreme irritability, Aseptic meningitis
- SN hearing loss,
GENITOURINARY SYSTEM
OTHER FINDINGS
- Erythema, induration at BCG inoculation site
- Anterior uveitis (mild)
- Desquamating rash in groin
FEVER
- The fever typically is high-spiking and remittent, with peak temperatures generally 39°C (102°F) and in many cases 40°C (104°F).
HANDS & FEET
- Erythema of the palms and soles or firm, sometimes painful induration of the hands or feet
- Desquamation of the fingers and toes
usually begins in the periungual region within 2 to 3 weeks after the onset of fever and may extend to include the palms and soles
- Approximately 1 to 2 months after the onset of fever, deep transverse grooves across the nails (Beau’s lines)
SKIN RASH
- Erythematous rash usually appears within 5 days of the onset of fever most common is a nonspecific, diffuse maculopapular eruption.
- Urticarial exanthem, a scarlatiniform rash, an erythroderma, an erythema-multiforme-like rash, or,rarely, a fine micropustular eruption
- Bullous and vesicular eruptions have not been described
EYES
- Bilateral conjunctival injection bulbar conjunctivae (sparing the limbus, an avascular zone around the iris)
- Exudate, conjunctival edema or corneal ulceration usually is painless
- Mild acute iridocyclitis
- Anterior uveitis
ORAL CAVITY
- Erythema, dryness, fissuring, peeling, cracking, and bleeding of the lips
- A “strawberry tongue” that is indistinguishable from that associated with streptococcal scarlet fever, with erythema and
- Prominent fungiform papillae
- Diffuse erythema of the oropharyngeal mucosae.